ABclonal Technology Co.,Ltd.

Business Type:Manufacturer

Main Products: antibodymolecular enzymesELISA KITProteinCRO servicesIVD materials

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Neutrophil Elastase (ELANE) Rabbit mAb

Medical & Health & Beauty Medicine

FOB Price:US$ 128.00 / Other

MOQ:20 Other

Payment Method : T/T 

Keywords:Synthetic Peptide ELA2  GE  HLE  HNE  NE  PMN-E  SCN1 

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Product Category: Medical & Health & Beauty > Medicine Trademark:
Product Package: Specifications:
Place of Origin: Port: 上海/广州
CatalogNo:A8953
Brand:ABclonal
ProductName:Neutrophil Elastase (ELANE) Rabbit mAb
Gene Symbol:ELANE
Alias:ELA2, GE, HLE, HNE, NE, PMN-E, SCN1
GeneId:1991
Swiss-Prot:P08246
Routing:Synthetic Peptide
Species:Human
ProteinWeight:29kDa
ObservedMW:30KDa
Source:Rabbit
Immunogen:A synthesized peptide derived from human Neutrophil Elastase (ELANE)
AntigenSeq:
CrossReactivity:Human, Mouse
Application:WB, IHC, IF
RecommandDilution:WB,1:500 - 1:2000|IHC,1:50 - 1:200|IF,1:50 - 1:200
Storage:Store at -20℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
PositiveSamples:THP-1,U-937
CelluarLocation:
ResearchArea:Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,Signal Transduction
Background:Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode structurally similar proteins. The encoded preproprotein is proteolytically processed to generate the active protease. Following activation, this protease hydrolyzes proteins within specialized neutrophil lysosomes, called azurophil granules, as well as proteins of the extracellular matrix. The enzyme may play a role in degenerative and inflammatory diseases through proteolysis of collagen-IV and elastin. This protein also degrades the outer membrane protein A (OmpA) of E. coli as well as the virulence factors of such bacteria as Shigella, Salmonella and Yersinia. Mutations in this gene are associated with cyclic neutropenia and severe congenital neutropenia (SCN). This gene is present in a gene cluster on chromosome 19. [provided by RefSeq, Jan 2016]
Note:Rabbit mab;20191111 第N批待上架;20210730


Contact Name: Miss ye zhao Contact Email: so****o@abclonal.com
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Address: Website: www.abclonal.com
ABclonal is an innovative growth company with the aim to provide reliable and cost-effective products and services for both basic and translational research in the cutting edges of biomedical science. Innovation is our DNA. ABclonal has established R&D centers in the worldwide with different focuses to support technical innovation and product development for protein science and molecular biology. We alway carefully listen to the opinions and feedback from talented cientists across the globe, quickly translate their needs into our product development pipeline, dedicating to develop the valuable research tools based on state-of-the-art technologies to meet the needs of innovation in a timely manner.

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ABclonal Technology Co.,Ltd.

Contact:ye zhao

Email:so****o@abclonal.com

Country:China

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