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Business Type: Manufacturer
Main Products:antibodymolecular enzymesELISA KITProteinCRO servicesIVD materials
ID:21121568811
Category: Medical & Health & Beauty Medicine
MOQ:20.00 Other
APLAID FCAS3 PLC-IV PLC-gamma-2
T/T
| CatalogNo: | A5182 |
| Brand: | ABclonal |
| ProductName: | PLC gamma 2 (PLCG2) Rabbit mAb |
| Gene Symbol: | PLCG2 |
| Alias: | APLAID, FCAS3, PLC-IV, PLC-gamma-2 |
| GeneId: | 5336 |
| Swiss-Prot: | P16885 |
| Routing: | Synthetic Peptide |
| Species: | Human |
| ProteinWeight: | 148kDa |
| ObservedMW: | 150KDa |
| Source: | Rabbit |
| Immunogen: | A synthesized peptide derived from human PLC gamma 2 (PLC gamma 2 (PLCG2)) |
| AntigenSeq: | |
| CrossReactivity: | Human, Mouse, Rat |
| Application: | WB, IF |
| RecommandDilution: | WB,1:500 - 1:2000|IF,1:50 - 1:200 |
| Storage: | Store at -20℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |
| PositiveSamples: | Raji |
| CelluarLocation: | |
| ResearchArea: | Angiogenesis,B Cell Receptor Signaling Pathway,Cancer,Cardiovascular,Cell Biology & Developmental Biology,Cytoskeleton,Cytoskeleton_Actins,Endocrine & Metabolism,ErbB-HER Signaling Pathway,Immunology & Inflammation,Lipid Metabolism,Lipid Metabolism_Hydrolysis,Lipids,MAPK-Erk Signaling Pathway,Protein phosphorylation,Signal Transduction |
| Background: | The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in this gene have been found in autoinflammation, antibody deficiency, and immune dysregulation syndrome and familial cold autoinflammatory syndrome 3. [provided by RefSeq, Mar 2014] |
| Note: | Rabbit mab;20191111 |
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