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ID:21121768972
Category: Medical & Health & Beauty Medicine
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Histone H3Synthetic PeptideRabbit pAbPolyclonal
T/T
| CatalogNo: | A16078 |
| Brand: | ABclonal |
| ProductName: | Acetyl-Histone H3-K4 Rabbit pAb |
| Gene Symbol: | Histone H3 |
| Alias: | H3.4;H3/g;H3FT;H3t;HIST3H3;Histone H3;HIST1H3A |
| GeneId: | 8290 |
| Swiss-Prot: | Q16695 |
| Routing: | Synthetic Peptide |
| Species: | Human |
| ProteinWeight: | 15kDa |
| ObservedMW: | 15kDa/17kDa |
| Source: | Rabbit |
| Immunogen: | A synthetic acetylated peptide around K4 of human Histone H3 (NP_003484.1). |
| AntigenSeq: | ARTKQ |
| CrossReactivity: | Human, Mouse, Rat, Other (Wide Range) |
| Application: | WB, IF, ChIP |
| RecommandDilution: | WB,1:500 - 1:2000|IF,1:50 - 1:100|ChIP,1:50 - 1:200 |
| Storage: | Store at -20℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |
| PositiveSamples: | NIH/3T3,C6 |
| CelluarLocation: | Chromosome,Nucleus |
| ResearchArea: | Signal Transduction,MAPK-Erk Signaling Pathway,MAPK-P38 Signaling Pathway,Epigenetics & Nuclear Signaling,Epigenetic Modifications,Acetylation |
| Background: | Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3. |
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