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Main Products:antibodymolecular enzymesELISA KITProteinCRO servicesIVD materials
ID:21122269059
Category: Medical & Health & Beauty Medicine
MOQ:20.00 Other
Synthetic peptideHistone H3 TriMethyl-Histone
T/T
| CatalogNo: | A16199 |
| Brand: | ABclonal |
| ProductName: | TriMethyl-Histone H3-K27 Mouse mAb |
| Gene Symbol: | Histone H3 |
| Alias: | H3.4;H3/g;H3FT;H3t;HIST3H3;Histone H3;HIST1H3A |
| GeneId: | 8290 |
| Swiss-Prot: | Q16695 |
| Routing: | Synthetic peptide |
| Species: | Human |
| ProteinWeight: | 15kDa |
| ObservedMW: | 16kDa |
| Source: | Mouse |
| Immunogen: | A synthetic methylated peptide corresponding to residues surrounding K27 of human histone H3 |
| AntigenSeq: | |
| CrossReactivity: | Human, Mouse, Rat, Other (Wide Range) |
| Application: | WB, IHC, IF, IP, ChIP |
| RecommandDilution: | WB,1:500 - 1:2000|IHC,1:50 - 1:200|IF,1:50 - 1:200|IP,1:50 - 1:200|ChIP,1:20 - 1:100 |
| Storage: | Store at -20℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |
| PositiveSamples: | HepG2,U-87MG,A-375,NIH/3T3,C2C12,C6 |
| CelluarLocation: | Chromosome,Nucleus, |
| ResearchArea: | Signal Transduction,MAPK-Erk Signaling Pathway,MAPK-P38 Signaling Pathway,Epigenetics & Nuclear Signaling,Epigenetic Modifications,Methylation |
| Background: | Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3. |
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