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ID:22010469729
Category: Medical & Health & Beauty Medicine
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Synthetic peptidecitrulline-Histone H3-R2/R8/R17 Rabbit pAbRabbit pAbpolyclonal
T/T
| CatalogNo: | A18298 |
| Brand: | ABclonal |
| ProductName: | citrulline-Histone H3-R2/R8/R17 Rabbit pAb |
| Gene Symbol: | Histone H3 |
| Alias: | H3/A;H3C2;H3C3;H3C4;H3C6;H3C7;H3C8;H3FA;H3C10;H3C11;H3C12;HIST1H3A |
| GeneId: | 8350 |
| Swiss-Prot: | P68431 |
| Routing: | Synthetic peptide |
| Species: | Human |
| ProteinWeight: | 15kDa |
| ObservedMW: | 17KDa |
| Source: | Rabbit |
| Immunogen: | A synthetic Peptide of citrulline-Histone H3-R2/R8/R17. |
| AntigenSeq: | |
| CrossReactivity: | Human, Mouse, Rat, Other (Wide Range) |
| Application: | WB, IF |
| RecommandDilution: | WB,1:500 - 1:2000|IF,1:50 - 1:200 |
| Storage: | Store at -20℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |
| PositiveSamples: | THP-1,Mouse kidney |
| CelluarLocation: | Chromosome,Nucleus, |
| ResearchArea: | Cell Biology & Developmental Biology,Cell Cycle,Immunology & Inflammation,MAPK-Erk Signaling Pathway,MAPK-P38 Signaling Pathway,NF-kB Signaling Pathway,Protein phosphorylation,Signal Transduction, |
| Background: | Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3. |

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