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Phospho-YAP1-S127 Rabbit pAbRabbit pAbpolyclonalantibody
T/T
| CatalogNo: | AP0489 |
| Brand: | ABclonal |
| ProductName: | Phospho-YAP1-S127 Rabbit pAb |
| Gene Symbol: | YAP1 |
| Alias: | COB1;YAP;YAP2;YAP65;YKI;YAP1 |
| GeneId: | 10413 |
| Swiss-Prot: | P46937 |
| Routing: | Synthetic peptide |
| Species: | Human |
| ProteinWeight: | 36kDa/48kDa/49kDa/50kDa/52kDa/53kDa/54kDa |
| ObservedMW: | 68kDa |
| Source: | Rabbit |
| Immunogen: | A synthetic phosphorylated peptide around S127 of human YAP1 (NP_001123617.1). |
| AntigenSeq: | AHSSP |
| CrossReactivity: | Human, Mouse, Rat |
| Application: | WB, IHC, IF |
| RecommandDilution: | WB,1:500 - 1:1000|IHC,1:50 - 1:200|IF,1:50 - 1:100 |
| Storage: | Store at -20℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |
| PositiveSamples: | NIH/3T3 |
| CelluarLocation: | Cytoplasm,Nucleus, |
| ResearchArea: | Epigenetics & Nuclear Signaling,Transcription Factors,Cancer,Signal Transduction,Kinase,Tyrosine kinases,Cell Biology & Developmental Biology,Hippo Signaling Pathway,Protein phosphorylation |
| Background: | This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms. |

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