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ID:22010469733
Medical & Health & Beauty Medicine
MOQ:20.00 Other
Phospho-mTOR-S2481 Rabbit pAbpolyclonalantibodies
T/T
| CatalogNo: | AP0490 |
| Brand: | ABclonal |
| ProductName: | Phospho-mTOR-S2481 Rabbit pAb |
| Gene Symbol: | mTOR |
| Alias: | FRAP;FRAP1;FRAP2;RAFT1;RAPT1;SKS;mTOR;MTOR |
| GeneId: | 2475 |
| Swiss-Prot: | P42345 |
| Routing: | Synthetic peptide |
| Species: | Human |
| ProteinWeight: | 288kDa |
| ObservedMW: | 289kDa |
| Source: | Rabbit |
| Immunogen: | A synthetic phosphorylated peptide around S2481 of human mTOR (NP_004949.1). |
| AntigenSeq: | IHSFI |
| CrossReactivity: | Human, Mouse |
| Application: | WB |
| RecommandDilution: | WB,1:500 - 1:2000 |
| Storage: | Store at -20℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |
| PositiveSamples: | C2C12 |
| CelluarLocation: | Cytoplasm,Cytoplasmic side,Endoplasmic reticulum membrane,Golgi apparatus membrane,Lysosome,Mitochondrion outer membrane,Nucleus,PML body,Peripheral membrane protein, |
| ResearchArea: | Epigenetics & Nuclear Signaling,Transcription Factors,DNA Damage & Repair,Translation Control,Regulation of eIF4 and p70 S6 Kinase,Cancer,Signal Transduction,Kinase,Serine/threonine kinases,PI3K-Akt Signaling Pathway,mTOR Signaling Pathway,ErbB-HER Signaling Pathway,Cell Biology & Developmental Biology,Autophagy,Cell Cycle,Cell cycle inhibitors,TGF-b-Smad Signaling Pathway,Endocrine & Metabolism,AMPK Signaling Pathway,Insulin Receptor Signaling Pathway,Warburg Effect,Endocrine and metabolic diseases,Obesity,Immunology & Inflammation,B Cell Receptor Signaling Pathway,T Cell Receptor Signaling Pathway,IL-6 Receptor Signaling Pathway,Cardiovascular,Angiogenesis,Heart,Cardiogenesis,Regulators,Protein phosphorylation |
| Background: | The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene. |
| Note: |
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