Acetyl-Histone H3-K36 Rabbit pAb

CatalogNo:A16077Brand:ABclonalProductName:Acetyl-Histone H3-K36 Rabbit pAbGene Symbol:Histone H3Alias:H3.4;H3/g;H3FT;H3t;HIST3H3;Histone H3;HIST1H3AGeneId:8290Swiss-Prot:Q16695Routing:Synthetic PeptideSpecies:HumanProteinWeight:15kDaObservedMW:17kDaSource:RabbitImmunogen:A synthetic acetylated peptide around K36 of human Histone H3 (NP_003484.1).AntigenSeq:GGVKKCrossReactivity:Human, Mouse, Rat, Other (Wide Range)Application:WB, IFRecommandDilution:WB,1:500 - 1:2000|IF,1:50 - 1:100Storage:Store at -20℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.PositiveSamples:HeLa,NIH/3T3CelluarLocation:Chromosome,NucleusResearchArea:Signal Transduction,MAPK-Erk Signaling Pathway,MAPK-P38 Signaling Pathway,Epigenetics & Nuclear Signaling,Epigenetic Modifications,AcetylationBackground:Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3.